More recently, Massa and coworkers derived an approximate analytical expression for the polarisability of a
cuboidal cell [27].
Finally, there are often zones of transition from the lepidic pattern to the invasive pattern, and in the zones of transition there is often a change in nuclear grade as well as cellular morphology to a more columnar than
cuboidal cell." (31(p55)) It is also important to remember that these terms must be used in their proper context.
Using antibodies against CK5/6 and p63, we were able to selectively label a distinct population of basal layer cells (Figure 5, B), corresponding to both the light and the electron microscopically identified
cuboidal cell layer that is in direct contact with the basal lamina (Figures 3 and 4).
The cell block revealed papillary & acinar structures with thin vascular connective tissue and covered by
cuboidal cells showing rounded vesicular nuclei.
Histopathologically, they consist of single or multiple dilated cysts in the dermis lined by an attenuated layer of double
cuboidal cells (indicative of their sweat duct derivation).
Histopathology demonstrated a large cyst lined by either papillary projections or a single layer of
cuboidal cells with mild to moderate atypia and surrounding solid tumor nests with focal cribriform pattern [Figure 3a-c].
The papillae were lined by
cuboidal cells with oval nuclei and prominent nuclear pseudo-inclusions (Figure 3a).
Inner layer is composed of larger columnar cells with decapitation and outer layer includes smaller
cuboidal cells. Fibrosis tissue souranding the tumor develops pseudocapsule in the periphery of the lesion.
In pseudopapillary areas, hyalinized and thickened vessels were covered by single or multiple layers of uniform
cuboidal cells [Figure 1]d.
Microscopically, the neoplasm is composed of cohesive, uniform,
cuboidal cells with minimal cytoplasm, arranged in nests and cribriform structures of variable size and shape, separated by moderate amount of fibrotic dense stroma (Figure 1).
It should be stressed, however, that the lumen of the rare and abortive tubular structures present is delimited by smaller
cuboidal cells expressing antigens CK7 (Figures 6(g) and 6(h)) and CK19 (Figures 6(i) and 6(j)).
The basal cell layer has
cuboidal cells which lack rete ridges, the cyst lining has buddings and is much folded.