Clioquinol


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Noun1.Clioquinol - drug used to treat certain fungal infection (as athlete's foot)
antifungal, antifungal agent, antimycotic, antimycotic agent, fungicide - any agent that destroys or prevents the growth of fungi
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References in periodicals archive ?
2-Mercaptoethanol (BME), zinc chloride (Zn[Cl.sub.2]), clioquinol (CQ), calcium disodium ethylene diamine tetraacetate (CaEDTA), Triton X-100, dimethylsulfoxide (DMSO), butylated hydroxyanisole (BHA), anti-mouse IgG-HRP, and anti-rabbit IgG-HRP were purchased from Sigma (MO, USA).
[3] The etiologies of myelopathy were MS, heredodegenerative, systemic lupus erythematosus, electrocution, spinal cord infarction, and clioquinol. In 23 (28.0%) patient's etiology could not be established.
Moreover, a 1-week treatment with the zinc chelator, clioquinol, decreased zinc staining in the hippocampus and reduced the number of progenitor cells.
Yan, "Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells" Journal of Biological Inorganic Chemistry, vol.
For example, clioquinol had good activity in guinea pigs but not in mice (Lewis et al., 1970, Tison., 1952).
Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells.