chimerism

Somatic mosaicism occurs when there is a spontaneous reversion mutation that can lead to a mixed chimerism of corrected and uncorrected bone marrow cells leading to stabilisation or correction of an FA patient's blood counts in the absence of any administered therapy.

Somatic mosaicism occurs when there is a spontaneous reversion mutation that can lead to a mixed chimerism of corrected and uncorrected bone marrow cells leading to stabilization or correction of an FA patient's blood counts in the absence of any administered therapy.

Monitoring post bone marrow transplant chimerism, the extent to which the donor cells have engrafted in the recipient, is essential to confirm stability or detect any signs of graft failure.

All patients receiving a therapeutic dose of Iomab-B in the SIERRA trial, either directly or via crossover, achieved successful engraftment without delay and donor chimerism by day 100 post-transplant without delay.

Chimerism is rare in humans; [approximately equal to] 40 cases have been reported.

The injectable gel scaffold material has the advantages of easy to plastic, can be mixed with cells evenly, and can be in good chimerism, safety and efficiency with the repair tissue.

Genetic variability within an organism can come about due to fusion between distinct individuals (chimerism) and/or through the accumulation of mutations, resulting in genetic mosaicism (Gill et al., 1995; Barki et at., 2002).

It may be inherited, or caused by genetic mosaicism, chimerism, disease, or injury.

Chimerism was evaluated in recipient peripheral blood cells by fluorescence in situ hybridization.

Chimerism occurs twice as often in lupus nephritis as in normal kidneys.

Chimerism results before and after eltrombopag treatment did not show any changes.