carnitine


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car·ni·tine

 (kär′nĭ-tēn′)
n.
A compound that functions in fatty acid metabolism by transporting fatty acids into mitochondria for energy production. It is naturally produced in the body and is present in many animal products, especially red meat. It is also sold as a dietary supplement for its purported health benefits.
[German Karnitin, from Karnin, a basic substance derived from meat, from Latin carō, carn-, flesh; see carnal.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

carnitine

(ˈkɑːnɪˌtaɪn)
n
a white betaine, C7H15NO3, found in the liver and required for transporting fatty acids from the cytosol into the mitochondria
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
Translations

carnitine

n carnitina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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References in periodicals archive ?
A basal diet (Table 1) was formulated without animal protein sources to minimize the presence of endogenous carnitine and supply the nutritional requirements of Nile tilapia (NRC, 2011).
DL-carnitine as supplementary levocarnitine source in plant-based diets to Nile tilapia (Oreochromis niloticus) fingerlings
Biochemically GCDH deficiency is characterized by a deposition of glutaric acid (GA, 3 hydroxyglutaric acid (3-OH-GA), glutaconic acid (less frequently) and glutaryl carnitine (C5DC) (7).
Glutaric Aciduria Type I Diagnosis Case with Normal Glutaryl Carnitine and Urine Organic Acid Analysis
Carnitine is an obligate cofactor that transfers long-chain fatty acids (FAs) into the mitochondria for the production of energy.
Biosynthesis of the essential fatty acid oxidation cofactor carnitine is stimulated in heart and liver after a single bout of exercise in mice
Her medical history included primary carnitine deficiency, a rare inherited metabolic disorder that causes cardiomyopathy, which was diagnosed as asymptomatic during her infancy following the death of her infant brother from cardiomyopathy related to the condition.
Primary Carnitine Deficiency: A Rare, Reversible Metabolic Cardiomyopathy
Comment: Carnitine plays a role in energy production by facilitating the transport of fatty acids into mitochondria.
L-Carnitine prevents frailty in elderly people
L-carnitine also plays a major role in regulating the mito-chondrial acetyl-CoA/CoASH ratio (12) and activating carnitine acyltransferases (CAT), which transport long-chain fatty acid across the mitochondrial inner membrane (13).
Effects of L-carnitine supplementation on metabolic utilization of oxygen and lipid profile among trained and untrained humans
Subsequently, a number of molecular studies revealed the presence of carnitine transporters in sperm, sertoli cells and epididymal epithelium and their importance in maintenance of male fertility.12-15 During the epididymal transit spermatozoa takes up free L-carnitine by passive diffusion and accumulates free as well as acetylated form.7
Relationship of seminal free L-Carnitine with functional spermatozoal characteristics: Results from an observational study conducted in a tertiary care hospital of Karachi, Pakistan
A study by Lerner Research Institute in the US showed that carnitine, a nutrient found in the meat, sets off gut microbe reactions that contribute to the development of heart disease.
Negative aspects for not eating meat
The latter compound is conjugated with carnitine to form 3-hydroxyisovalerylcarnitine, detected by acylcarnitine analysis using MS/MS.
A Case of Increased C5-OH Acylcarnitine
DeFelice's journey with carnitine, he faced every barrier in our medical discovery system.
Prominent physician proposes a can-do way to reduce health care costs--by finding cures
Carnitine can be synthesized endogenously from essential amino acids; lysine and methionine.
Screening of free carnitine and acylcarnitine status in children with familial Mediterranean fever

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